Stable tissue-simulating phantoms with various water and lipid contents for diffuse optical spectroscopy
| Autor: | Tetsuya Mimura, Hatsuko Nasu, Norihiro Suzuki, Etsuko Ohmae, Harumi Sakahara, Maho Hayashi, Yutaka Yamashita, Hiroko Wada, Nobuko Yoshizawa, Yukio Ueda, Hiroaki Suzuki, Kenji Yoshimoto, Hiroyuki Ogura, Shu Homma |
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| Rok vydání: | 2018 |
| Předmět: |
Materials science
Absorption spectroscopy Scattering equipment and supplies 01 natural sciences Atomic and Molecular Physics and Optics Imaging phantom Article 010309 optics body regions 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Attenuation coefficient 0103 physical sciences Emulsion Medical imaging Spectroscopy Absorption (electromagnetic radiation) Biotechnology Biomedical engineering |
| Zdroj: | Biomedical optics express. 9(11) |
| ISSN: | 2156-7085 |
| Popis: | We introduced a method for producing solid phantoms with various water-to-lipid ratios that can simulate the absorption, and to some extent the scattering characteristics of human breast tissue. We also achieved phantom stability for a minimum of one month by solidifying the emulsion phantoms. The characteristics of the phantoms were evaluated using the six-wavelength time-domain diffuse optical spectroscopy (TD-DOS) system we developed to measure water and lipid contents and hemoglobin concentration. The TD-DOS measurements were validated with a magnetic resonance imaging system. |
| Databáze: | OpenAIRE |
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