Synthesis of (pyrimidin-4-yloxy)- and (pyrimidin-3-yl)acetyl azides and their rearrangement to carbamates and ureas

Autor:	Milda M. Burbuliene, Povilas Vainilavicius, Zana Kacnova, Virginija Jakubkiene
Rok vydání:	2010
Předmět:	lcsh:QD241-441 chemistry.chemical_compound lcsh:Organic chemistry chemistry Organic Chemistry Nitrosation Hydrochloric acid Phenols Sodium nitrite Medicinal chemistry Curtius rearrangement
Zdroj:	ARKIVOC, Vol 2010, Iss 11, Pp 39-48 (2010)
ISSN:	1551-7012
DOI:	10.3998/ark.5550190.0011.b04
Popis:	On nitrosation of (pyrimidin-4-yloxy)and (pyrimidin-3-yl)acetohydrazides 2, 3 with sodium nitrite in diluted hydrochloric acid at 0-5 °C the corresponding (pyrimidinyl)acetyl azides 5, 6 were prepared. Azides 5, 6 undergo Curtius rearrangement in the reactions with alcohols, phenols, arylamines or water to give carbamates 7-9, 11-14 or ureas 15-21.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab29fabf35837b8adbb350af450ed4f0 https://doi.org/10.3998/ark.5550190.0011.b04 Zobrazit plný text záznamu Plný text ve formátu PDF