Nine New Dammarane Saponins fromGynostemma pentaphyllum
| Autor: | Lihong Hu, Yinan Zhang, Feng Yin, Zheng-Yi Yang |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Magnetic Resonance Spectroscopy
Antineoplastic Agents Bioengineering Biochemistry chemistry.chemical_compound Cell Line Tumor medicine Humans Gynostemma pentaphyllum Stomach cancer Molecular Biology Cell Proliferation Antitumor activity Molecular Structure biology Traditional medicine Chemistry Dammarane General Chemistry General Medicine medicine.disease biology.organism_classification Triterpenes Gynostemma Molecular Medicine Cucurbitaceae |
| Zdroj: | Chemistry & Biodiversity. 3:771-782 |
| ISSN: | 1612-1880 1612-1872 |
| DOI: | 10.1002/cbdv.200690079 |
| Popis: | Nine new dammarane saponins, 1-9, were isolated from the MeOH extract of the aerial part of Gynostemma pentaphyllum, an edible plant of the Cucurbitaceae family, that grows wildly in China. Their structures were elucidated by 1D- and 2D-NMR analysis, as well as by chemical degradation. Aglycons 21,24-cyclopentyldammar-25-ene of 6 and 7, and 21,24-cyclopentyldammarane of 8 and 9, were novel. Compounds 1, 4, and 8 showed moderate antitumor activities against stomach cancer cells SGC-7901 and liver cancer cells BEL-7402. |
| Databáze: | OpenAIRE |
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