Genetic variation of 20 autosomal STRs in Jats belonging to Delhi, India
| Autor: | Shivani Dixit, K P S Kushwaha, Tanya Chauhan, R.K. Kumawat, Lalita, Pankaj Shrivastava |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Paternity Index Population India Locus (genetics) Biology 01 natural sciences Pathology and Forensic Medicine Loss of heterozygosity 03 medical and health sciences 0302 clinical medicine Gene Frequency Genetic variation Ethnicity Humans 030216 legal & forensic medicine Allele education Allele frequency Alleles Genetics education.field_of_study Genetic diversity Polymorphism Genetic 010401 analytical chemistry Genetic Variation 0104 chemical sciences Female Microsatellite Repeats |
| Zdroj: | International Journal of Legal Medicine. 135:771-773 |
| ISSN: | 1437-1596 0937-9827 |
| DOI: | 10.1007/s00414-020-02423-9 |
| Popis: | The present study based on 20 autosomal STR polymorphism reveals the genetic diversity of the Jat population of Delhi, India (n = 120). A total of 240 alleles were observed for this study. The allele frequency ranged from 0.004 to 0.508. The studied loci followed the Hardy-Weinberg equilibrium (HWE), and the heterozygosity ranged from 0.658 to 0.908. The locus Penta-E was found the most polymorphic and discriminating in the studied population with the value 0.910 and 0.981, respectively, whereas the locus TPOX was found least polymorphic and discriminating with the value 0.612 and 0.833, respectively. The combined paternity index (CPI) was 1.46 × 109, and the probability of match (CPm) was 2.68 × 10-25 for all 20 autosomal STR loci. The generated data adds to the Indian population database. It will be used for forensic purposes and in other population-based genetic studies. |
| Databáze: | OpenAIRE |
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