Combined therapy with inhaled nitric oxide and intravenous prostacyclin in an infant with alveolar-capillary dysplasia
| Autor: | S Z Ruyle, D. Dunbar Ivy, John Kinsella, Elizabeth H. Thilo, Steven H. Abman, Flaminia M. Torielli, Thomas A. Parker |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Alveolar capillary dysplasia Hypertension Pulmonary Prostacyclin Pulmonary Artery Nitric Oxide Critical Care and Intensive Care Medicine Infant Newborn Diseases Nitric oxide chemistry.chemical_compound Fatal Outcome medicine Humans Antihypertensive Agents Inhalation business.industry Respiratory disease Infant Newborn medicine.disease Epoprostenol Pulmonary hypertension chemistry Echocardiography Pulmonary Veins Dysplasia Anesthesia Complication business medicine.drug |
| Zdroj: | American Journal of Respiratory and Critical Care Medicine. 155:743-746 |
| ISSN: | 1535-4970 1073-449X |
| DOI: | 10.1164/ajrccm.155.2.9032222 |
| Popis: | Severe persistent pulmonary hypertension of the newborn (PPHN) remains a significant cause of neonatal morbidity and mortality with limited effective treatment options. We present the first case of a neonate with PPHN treated concurrently with inhaled nitric oxide (iNO) and intravenous prostacyclin (PGI2). He ultimately was diagnosed with alveolar-capillary dysplasia, a rare and fatal cause of pulmonary hypertension. However, his partial response to treatment demonstrates a possible role for combined therapy with iNO and PGI2 in infants with severe PPHN. |
| Databáze: | OpenAIRE |
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