Normative Heart-Rate Corrected Values for Repolarisation Length From Holter Recordings in Children and Adults
| Autor: | Jian Li, Jonathan R. Skinner, Kathryn E Waddell-Smith, Halina Hinds, Alexandra A. Chaptynova, Jackie Crawford |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Pulmonary and Respiratory Medicine Holter monitor medicine.medical_specialty Adolescent Population 030204 cardiovascular system & hematology QT interval Young Adult 03 medical and health sciences 0302 clinical medicine Heart Conduction System Heart Rate Internal medicine Healthy volunteers Heart rate medicine Humans cardiovascular diseases 030212 general & internal medicine Child education Aged education.field_of_study medicine.diagnostic_test business.industry Infant Arrhythmias Cardiac Repeatability Middle Aged Holter recording Child Preschool Healthy individuals Electrocardiography Ambulatory cardiovascular system Cardiology Cardiology and Cardiovascular Medicine business circulatory and respiratory physiology |
| Zdroj: | Heart, Lung and Circulation. 29:1469-1475 |
| ISSN: | 1443-9506 |
| DOI: | 10.1016/j.hlc.2019.12.006 |
| Popis: | Normative values for heart-rate corrected repolarisation length are not available in children and are scarce in adults. We wished to define repeatability and normative values of Holter recording measurements of repolarisation length in healthy individuals using a commercially available system, and compare measurements with those from 12-lead electrocardiograms (ECGs).Twenty-four-hour (24-) Holter recordings were made on 99 Healthy volunteers: 52 children (7 months to 14 years) and 47 adults (≥15 yrs). Mean and peak values of QTc, and RTPc (R-wave to peak T-wave) were assessed. Bazett heart rate correction was employed for each measurement and only heart rates between 40 and 120 bpm were analysed. The end of the T-wave was defined from the zero-crossing point. QTc was also determined from 12-lead ECGs from the same population by manual measurement recording the longest QTc of leads 2 and V5. The tangent technique was used to define the end of the T-wave.Interobserver repeatability: mean QTc ±15 ms (CI 3.5%), peak QTc ±25 ms (CI 4.5%), mean RTPc ±3 ms (CI 1%), peak RTPc ±44 ms (CI 11%). Mean values were very similar for15 years and all females and were therefore amalgamated: mean (±2 SD); mean QTc 424 ms (394-454), mean RTPc 291ms (263-319). Values were lower in males ≥15 years; (mean QTc 408 ms (370-446), p0.01; mean RTPc 274 ms (234-314), p0.01. The highest mean QTc value was 467 ms in an adult female. QTc from 12-lead ECG: females15 years 409 ms (384-434) males15 years 408 ms (383-433), females ≥15 years 426 ms (401-451), males ≥15 years 385 ms (362-408).Holter measurements of mean QTc and RTPc are highly repeatable. Males ≥15 years have shorter mean repolarisation length over 24 hours than males15 years and all females. Mean QTc Holter values were on average 15-17 ms longer than QTc from 12-lead ECGs except in females15 years. |
| Databáze: | OpenAIRE |
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