The lymphocyte/monocyte ratio and red blood cell transfusion during radical retropubic prostatectomy

Autor: Jihion Yu, Young-Kug Kim, Yongsoo Lee, Jun-Young Park, Bumjin Lim, Jai-Hyun Hwang, Jiwoong Lee
Rok vydání: 2021
Předmět:
Zdroj: Journal of Anesthesia
ISSN: 1438-8359
0913-8668
DOI: 10.1007/s00540-021-03008-5
Popis: Purpose Despite improvements of strategy in radical retropubic prostatectomy, blood loss is still a major concern. The lymphocyte/monocyte (LM) ratio is a prognostic indicator for various diseases. We identified the risk factors, including the LM ratio, for red blood cell (RBC) transfusion during radical retropubic prostatectomy. Methods This retrospective study assessed patients who underwent radical retropubic prostatectomy between March 2009 and December 2020. To determine the risk factors for RBC transfusion, a multivariate logistic regression analysis was conducted. A receiver operating characteristic (ROC) curve analysis was also performed. Postoperative outcomes, including acute kidney injury (AKI), hospitalization duration, and intensive care unit (ICU) admission, were also evaluated. Results Among 1302 patients, 158 patients (12.1%) received an intraoperative RBC transfusion. Multivariate logistic regression analysis demonstrated that the risk factors for RBC transfusion were the LM ratio, hemoglobin, 6% hydroxyethyl starch amount, and positive surgical margin. The area under the ROC curve of LM ratio was 0.706 (cut-off = 4.3). The LM ratio at ≤ 4.3 was significantly related to transfusion in multivariate-adjusted analysis (odds ratio = 4.598, P
Databáze: OpenAIRE
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