COVID-19 Vaccine Hesitancy in Patients on Dialysis in Italy and France

Autor: H. Fessi, Alessio Pili, Ciro Esposito, Giorgina Barbara Piccoli, Antoine Chatrenet, Sophie Blanchi, Massimo Torreggiani, Nicola Lepori, Elisabetta Versino, Giuseppe Sileno, Antioco Fois, Giovanna Bianco, Antonello Pani, Linda Njandjo, Béatrice Mazé, Vittoria Esposito, Gianfranca Cabiddu, P.A. Michel, Marta Arazzi
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Kidney International Reports
Popis: Introduction Patients on dialysis (HDPs) are a category at high risk from COVID-19 and thus a high-priority group for vaccination. COVID-19 vaccine hesitancy has been a concern since the availability of the first vaccine. The objective of this study was to determine hesitancy rates and factors associated with hesitancy toward COVID-19 vaccination in HDP. Methods HDP were surveyed with an ad hoc questionnaire in 4 large dialysis facilities in Europe: Le Mans and Paris, in France, and Cagliari and Pavia, in Italy. The questionnaire explored different domains associated with vaccine hesitancy, such as perception of disease severity, sources of information about the vaccine and the disease, and confidence in the health care system. Results A total of 417 patients (average age 69 years, 60% men) agreed to answer the questionnaire. Hesitancy was associated with younger age (P = 0.003), lower perception of disease severity (P < 0.001) and vaccine efficacy (P < 0.001), and lower trust in vaccination (P < 0.001) and in the health care system and scientists (P < 0.001) in the univariate analysis. In the multivariate models, concerns about side effects (P = 0.004) and vaccine efficacy (P < 0.001) and living in France (P = 0.04) remained associated with higher vaccine hesitancy, whereas having received an influenza vaccine (P = 0.032) and trusting scientists (P = 0.032) were associated with a more positive attitude toward vaccination. Conclusions HDPs have a good understanding of the risks associated with COVID-19. Vaccine hesitancy was not associated with educational level, age, or gender but rather with lack of confidence in vaccine efficacy and concerns about safety. HDPs were quite skeptical about the health care system but generally trusted scientists.
Databáze: OpenAIRE