OCT Angiography of the Choriocapillaris in Central Serous Chorioretinopathy: A Quantitative Subgroup Analysis

Autor: Milena Stech, Bastian Grundel, Michael Reich, Stefan J. Lang, Daniel Böhringer, Clemens Lange, Hansjürgen Agostini, Sabine Reichl, Anima Bühler, Christoph Ehlken, Andreas Stahl, Bertan Cakir
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Ophthalmology and Therapy, Vol 8, Iss 1, Pp 75-86 (2019)
Ophthalmology and Therapy
ISSN: 2193-6528
2193-8245
DOI: 10.1007/s40123-018-0159-1
Popis: Introduction To quantify optical coherence tomography angiography (OCTA) signal changes at the level of the choriocapillaris (CC) in patients with different stages of central serous chorioretinopathy (CSC) and to explore any correlation between subretinal fluid (SRF) and retinal pigment epithelium (RPE) alterations and the OCTA CC signal. Methods One hundred one CSC eyes and 42 healthy control eyes were included in this retrospective study. CSC patients were allocated into four groups: acute, non-resolving, chronic atrophic and inactive CSC. CC OCTA images (AngioPlex®, Zeiss) were automatically quantified using an image-processing algorithm. Spatial correlation analysis of OCTA signals was performed by overlapping macular edema heatmaps and fundus autofluorescence images with corresponding OCTA images. Results Active CSC subgroups demonstrated significantly more increased and decreased flow pixels in the CC compared with controls (p
Databáze: OpenAIRE
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