Breast Conservation Therapy with Tumor Bed Irradiation Alone in a Selected Group of Patients with Stage I Breast Cancer
| Autor: | Engikolai C. Krishnan, Leela Krishnan, Ossama Tawfik, William R. Jewell |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Brachytherapy Breast Neoplasms Pilot Projects Interstitial irradiation Mastectomy Segmental Disease-Free Survival Internal Medicine medicine Breast-conserving surgery Humans Tumor bed Aged Neoplasm Staging Aged 80 and over business.industry Lumpectomy Axillary Node Dissection Middle Aged Iridium Radioisotopes Surgery Radiation therapy Carcinoma Intraductal Noninfiltrating Treatment Outcome Oncology Female business Breast conservation therapy Stage I breast cancer |
| Zdroj: | The Breast Journal. 7:91-96 |
| ISSN: | 1524-4741 1075-122X |
| DOI: | 10.1046/j.1524-4741.2001.007002091.x |
| Popis: | Radiotherapy after breast-conserving surgery increases local control. We tested the feasibility of limited surgery with tumor bed irradiation only with 192Ir in a selected group of patients with stage I breast cancer. Twenty-five breasts in 24 women more than 60 years old with low- or intermediate-grade stage I tumors were treated with placement of interstitial catheters at the time of lumpectomy and axillary node dissection. This procedure was followed by after-loading with low-dose 192Ir to deliver 20–25 Gy to the tumor bed over 24–48 hours. There were neither local recurrences in the breast nor distant recurrences at a median follow-up of 47 months (range 25–90 months). Cosmetic appearance ranged from very good to excellent. There were no long-term complications. It is feasible to treat a select group of patients with tumor bed irradiation, using relatively low doses of interstitial irradiation, with excellent local control and no significant morbidity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|