Comparison of the Effects of Low-Level Laser Therapy and Ozone Therapy on Bone Healing
| Autor: | Hilal, Alan, Nigar, Vardi, Cem, Özgür, Ahmet Hüseyin, Acar, Ahmet, Hüseyin, Ümit, Yolcu, Derya Ozdemir, Doğan |
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| Přispěvatelé: | [Alan, Hilal -- Ozgur, Cem -- Yolcu, Umit] Inonu Univ, Fac Dent, Dept Oral & Maxillofacial Surg, TR-44280 Malatya, Turkey -- [Vardi, Nigar] Inonu Univ, Fac Dent, Dept Histol & Embriol, Malatya, Turkey -- [Huseyin, Ahmet] Bezmialem Vakif Univ, Fac Dent, Dept Oral & Maxillofacial Surg, Istanbul, Turkey -- [Dogan, Derya Ozdemir] Cumhuriyet Univ, Fac Dent, Dept Prostodont, Sivas, Turkey |
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Time Factors ALAN H. VARDI N. Ozgur C. Huseyin A. YOLCU Ü. ÖZDEMİR DOĞAN D. -Comparison of the Effects of Low-Level Laser Therapy and Ozone Therapy on Bone Healing- JOURNAL OF CRANIOFACIAL SURGERY cilt.26 2015 medicine.medical_treatment Osteocalcin Urology Connective tissue Bone healing Ozone Laser therapy Osteogenesis medicine Animals Combined Modality Therapy rat Bone formation Femur Low-Level Light Therapy Rats Wistar Low level laser therapy Inflammation Wound Healing Osteoblasts biology business.industry General Medicine Ozone therapy Rats low-level laser therapy ozone Durapatite medicine.anatomical_structure Otorhinolaryngology Connective Tissue Bone Substitutes biology.protein Surgery Bone Diseases Lasers Semiconductor business |
| Zdroj: | Journal of Craniofacial Surgery. 26:e396-e400 |
| ISSN: | 1049-2275 |
| Popis: | WOS: 000369611000010 PubMed ID: 26167994 This study aims to compare the effect of low-level laser therapy (LLLT) and ozone therapy on the bone healing. Thirty-six adult male Wistar albino rats were used for this study. Monocortical defects were shaped in right femur of all rats. Defects were filled with nano-hydroxyapatite graft. The animals were divided into 3 groups and each group was than divided into 2 subgroups. Then, LLLT with a diode laser was applied to the first group (G1), ozone therapy was applied to the second group (G2), and no treatment was applied to the third group as a control group (G3). Animals were sacrificed after 4th and 8th weeks and the sections were examined to evaluate the density of the inflammation, the formation of connective tissue, the osteogenic potential, and osteocalcin activity. As a result, there were no significant differences among the groups of 4 weeks in terms of new bone formation. In the immunohistochemical assessment, the number of osteocalcin-positive cells was higher in the laser group compared to the other group of 4 weeks; this difference was statistically significant in the LLLT and ozone groups (P < 0.05). Histomorphometric assessment showed that the new bone areas were higher in the LLLT and ozone groups; furthermore, there was a statistically significant difference in the LLLT in comparison with the control group at 8th week (P < 0.05). At the same time immunohistochemical assessment showed that osteocalcin-positive cells were considerably higher in G2 than G1 at 8th week (P < 0.05). The findings of this study may be the result of differences in the number of treatment sessions. Further studies are therefore needed to determine the optimal treatment modality. Scientific Research Council of Inonu University [2012-156] This project was funded by the Scientific Research Council of Inonu University (2012-156). |
| Databáze: | OpenAIRE |
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