| Autor: |
James T. Rutka, Gelareh Zadeh, Michael D. Taylor, William L. Stanford, Cynthia Hawkins, Gregory N. Fuller, Paul S. Mischel, Michael S. Taccone, Vijay Ramaswamy, Patricia Rakopoulos, Danielle Mackenzie, Stacey-Lynn Krumholtz, Christian A. Smith, Alan Chalil, Rob A. Cairns, Susan Younger, Marc Remke, Xi Huang, Brian Golbourn, Sameer Agnihotri |
| Rok vydání: |
2023 |
| Popis: |
Supplemental Figure 1: Related to Figure 1: Characterization of Gene-Trapped Clones Supplemental Figure 2 Related to Figure 2: PINK1 alters normal astrocyte metabolism Supplemental Figure 3 Related to Figure 2: PINK1 alters normal astrocyte metabolism Supplemental Figure 4: Related to Figure 3: PINK1 alters normal astrocyte metabolism and stabilizes HIF1a Supplemental Figure 5: Related to Figure 3: PINK1 overexpression stops GBM cell growth and inhibits glycolysis. Supplemental Figure 6: Related to Figure 3: PINK1 overexpression inhibits glycolysis. Supplemental Figure 7: Related to Figure 3: PINK1 overexpression inhibits glycolysis. Supplemental Figure 8: Related to Figure 4: Selective targeting in PINK1 expressing GBM cells leads to reduced viability Supplemental Figure 9: Related to Figure 4: Targeting of PINK1 in GBM cells leads to reduced colony formation and caspase activity Supplemental Figure 10: Related to Figure 5 and 6. PINK1 expression in vivo. Supplemental Table 1: Genes identified from gene-trap screen. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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