The role of a commercial latex agglutination test in the diagnosis of group B streptococcal infection in neonates
| Autor: | M. Thore, S. Thid, G. Hedin, S. Ringertz, G. Faxelius, Y. Öhrner, A. Schwan, S. Schröder, H. Johnsson |
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| Rok vydání: | 1991 |
| Předmět: |
Male
Group B Streptococcal Infection Urine Sensitivity and Specificity Group B Microbiology Streptococcus agalactiae Leukocyte Count Streptococcal Infections Medicine Humans Positive test Prospective Studies biology business.industry Infant Newborn General Medicine Streptococcaceae biology.organism_classification Latex fixation test Neonatal infection C-Reactive Protein Pediatrics Perinatology and Child Health Female Latex test business Latex Fixation Tests |
| Zdroj: | Acta paediatrica Scandinavica. 80(2) |
| ISSN: | 0001-656X |
| Popis: | An open prospective multicenter study was conducted in order to evaluate the Wellcogen Strep B latex agglutination test in the diagnosis of group B streptococcal (GBS) infections in neonates. Twenty-three (5.9%) of 391 urine specimens and 5 (1.2%) of 404 sera assayed were positive. The results of the urine tests corresponded to a sensitivity of 0.78 for bacteremic, 0.50 for non-bacteremic and 0.53 for all GBS associated (bacteremic, non-bacteremic and suspected) infections. After 20-25-fold concentration of urine specimens the sensitivity increased to 1.0 for bacteremic, 0.67 for non-bacteremic and 0.78 for all GBS associated infections. The specificity of the test was high (0.93 for concentrated urines), and the predictive value of a positive test (Pvpos) was 0.68. A positive latex test was highly predictive of positive surface cultures for GBS (Pv pos = 0.83 after concentration). |
| Databáze: | OpenAIRE |
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