Hypercalcemia preferentially occurs in unusual forms of childhood non-hodgkin's lymphoma, rhabdomyosarcoma, and Wilms' tumor. A study of 11 cases
| Autor: | Marie-France Tournade, Chantal Kalifa, Olivier Hartmann, Leblanc A, Catherine Patte, Jean Lemerle, J. M. Caillaud, Françoise Flamant |
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| Rok vydání: | 1984 |
| Předmět: |
Male
Cancer Research Pathology medicine.medical_specialty Adolescent Lymphoma Childhood Non-Hodgkin's Lymphoma Bone Neoplasms Malignancy Wilms Tumor Antineoplastic Combined Chemotherapy Protocols Rhabdomyosarcoma medicine Humans Neoplasm Metastasis Child Kidney business.industry Lymphoblastic lymphoma Infant Wilms' tumor Prognosis medicine.disease Kidney Neoplasms medicine.anatomical_structure Oncology El Niño Hypercalcemia Female Bone marrow business |
| Zdroj: | Cancer. 54:2132-2136 |
| ISSN: | 1097-0142 0008-543X |
| Popis: | Unusual clinical, radiologic, or histologic findings were found in 11 of 17 cases of hypercalcemia associated with childhood tumors. Four children had undifferentiated lymphoblastic lymphoma with extensive bone involvement, but no visceral or neurologic involvement. At diagnosis, four adolescents with rhabdomyosarcoma had numerous metastases, particularly in the breasts and bone marrow. Three infants had renal tumor without bone metastases. Histologically, their tumors differed from classical nephroblastoma and resembled the malignant rhabdoid tumors of the kidney. These findings allow individualization of three distinct groups of tumors with unusual features which may suggest the presence of hypercalcemia. These tumors appear to have a poor prognosis since all patients but one died of their malignancy. |
| Databáze: | OpenAIRE |
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