A review of research efforts to address the 2008 ACEP guideline for mild traumatic brain injury
| Autor: | Anya Mazur-Mosiewicz, Tyler Combs, Michelle Farabough, Matt Vassar, Joshua Gordon, Donald Sanders, Michael Schiesel, Jack Manquen |
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| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
media_common.quotation_subject Poison control Suicide prevention Occupational safety and health Evidence-Based Emergency Medicine 03 medical and health sciences 0302 clinical medicine Injury prevention medicine Humans Quality (business) Intensive care medicine Brain Concussion media_common business.industry Human factors and ergonomics 030208 emergency & critical care medicine General Medicine Guideline Clinical trial Research Design Practice Guidelines as Topic Emergency Medicine Guideline Adherence Health Services Research business Emergency Service Hospital Systematic Reviews as Topic |
| Zdroj: | The American journal of emergency medicine. 37(1) |
| ISSN: | 1532-8171 |
| Popis: | Background The objective of this study was to evaluate the temporal relationship between clinical practice guideline development and subsequent research performed, with the goal of providing more data on areas of sparse evidence that serve to underlie guideline recommendations. We aimed to assess the quality of current research efforts to address the American College of Emergency Physicians guideline and to provide suggestions for future research of mild traumatic brain injury. Methods We identified clinical practice guideline recommendations with low levels of underlying evidence and searched ClinicalTrials.gov and the World Health Organization's International Clinical Trial Registry Portal to determine whether subsequent research has reflected an effort to address guideline recommendations. Results Few currently registered clinical trials attempt to focus on clinical practice guideline recommendations where the basis of evidence is weak, and even fewer might benefit future iterations of the guideline due to multiple problems in study design and reporting. Conclusions The amount of research dedicated to investigation of mild traumatic brain injury continues to be sparse and of poor quality. Study results should always be posted, even if the null hypothesis is confirmed. Efforts to improve the evidence base of a guideline should be realized by designing studies that directly assess and speak to the questions posed by guideline authors. |
| Databáze: | OpenAIRE |
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