Long-term care and management of Wilson's disease in the GDR

Autor: Roland Siegemund, Barbara Teichmann, H. Kuhn, Gerhard Kallwellis, Dietmar Biesold, Konstanze Tinschert, Helmut Willgerodt, Kerstin Lakner, Hans Bachmann, Gerhard Mühlau, Joachim Lössner, Bernhard Kunath, Volker Schmehl, Beta Hitzschke, Valentin Wieczorek
Rok vydání: 1989
Předmět:
Zdroj: European neurology. 29(6)
ISSN: 0014-3022
Popis: Diagnosis, long-term management and family investigations of Wilson's disease are provided by selected clinical institutions in the GDR. From 187 patients detected since 1949, 111 are alive. In spite of the principal effectiveness of penicillamine treatment, confirmed by the disappearance of most of the central nervous system symptoms and successful professional rehabilitation of many patients, insufficient therapeutic discipline, psychosocial disturbances and penicillamine side-effects forcing its substitution by zinc or triethylenetetramine dihydrochloride in 14 cases need our further attention.
Databáze: OpenAIRE