Long-term monitoring of renal transplant patients by a CUSUM test on serum creatinine
| Autor: | Gilberto Calconi, Cristina Tessarin, Antonio Piccoli, Matilde Filippini, Arturo Borsatti, Mauro Dugo, Gianfranco Rizzoni |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1987 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Adolescent Cusum test Urology Renal function Kidney Function Tests Kidney transplant Sensitivity and Specificity chemistry.chemical_compound medicine Humans Child Monitoring Physiologic Retrospective Studies Kidney Creatinine urogenital system business.industry General Medicine Middle Aged Kidney Transplantation humanities Surgery medicine.anatomical_structure chemistry Nephrology Renal transplant Long term monitoring Child Preschool Data Interpretation Statistical Female sense organs business |
| Popis: | A retrospective clinical assessment of kidney function change was performed on 38 kidney transplant patients over a median follow-up period of 128 weeks. Full records of the patients' course were available to the clinician, while only the serum creatinine series of each patient was supplied to the computer on which a bilateral CUSUM test was implemented. The frequency of change assessed by the clinician was 146 out of 2,688 patient-weeks. The computer identified the function changes with 84.9% sensitivity and 94.3% specificity and the function deteriorations attributed to rejection with 88.9% sensitivity and 97.2% specificity. Thus we suggest an efficient long-term monitoring of the graft function with this simple and reliable statistical technique. |
| Databáze: | OpenAIRE |
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