Covid-19: loss of bridging between innate and adaptive immunity?
| Autor: | Vishal Rao, Mufti Suhail Sayeed, Gururaj Rao, Jyothsna Rao, Gururaj Arakeri, Sachin H Jadhav, Peter A. Brennan, Anand Subash |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Risk Bridging (networking) Coronavirus disease 2019 (COVID-19) Adaptive immunity Severe disease Disease Biology Article 03 medical and health sciences 0302 clinical medicine Immune system Age groups Humans COVID-19 Serotherapy Innate immunity Innate immune system Immunization Passive COVID-19 General Medicine Th1 Cells Acquired immune system Immunity Innate 030104 developmental biology Treatment Outcome SARS-CoV2 Cytokines Interferons Interferons (IFNs) Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Medical Hypotheses |
| ISSN: | 1532-2777 0306-9877 |
| Popis: | COVID-19 has spread to most countries in the world. However, there are some striking differences in how COVID-19 is behaving in different age groups. While data on COVID-19 is limited, children appear to be less susceptible to severe disease. These unique characteristics may be considered as a potential link to understanding the immune system and response in COVID-19 and lead to an effective cure to the disease. We suggest a possible role of loss of bridging between innate and adaptive immunity in COVID-19 and a potential treatment modality also discussed. |
| Databáze: | OpenAIRE |
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