Sepsis secondary to multifocal Enterococcus faecium infection: A case report
| Autor: | Xiao-qing Huang, Jiekun Xu, Minjie Mao, Lei Pan, Xiao-bo Ji, Caihong Wang, Xiaohong Pan, Junke Qiu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Tuberculosis Secondary infection Enterococcus faecium Sepsis Diagnosis Differential sepsis 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Humans 030212 general & internal medicine Clinical Case Report Tuberculosis Pulmonary Gram-Positive Bacterial Infections Aged immunocompromised host Voriconazole biology Teicoplanin business.industry General Medicine biochemical phenomena metabolism and nutrition medicine.disease biology.organism_classification Anti-Bacterial Agents chemistry tuberculosis 030220 oncology & carcinogenesis Bacteremia Linezolid Female business medicine.drug Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 |
| Popis: | Introduction: Nosocomial Enterococcus faecium (E faecium) infections are common among immunocompromised patients; however, sepsis caused by E faecium is rarely encountered in the clinical setting. Patient concerns: A 69-year-old woman with a previous history of tuberculosis (TB), developed symptoms of recurrent fever, paroxysmal cough, and exertional dyspnea for over 2 months before she presented to the hospital. Diagnosis: The patient was initially misdiagnosed with recurrent TB, and did not respond to anti-TB therapy. Culture results of blood, endotracheal necrotic tissue, and urine confirmed a diagnosis of multifocal E faecium infection. Interventions: On definitive diagnosis, the patient received intensive antimicrobial combination treatment with linezolid, teicoplanin, caspofungin, and voriconazole on the basis of antimicrobial susceptibility results. Outcomes: After transient improvement, the patient's condition deteriorated due to secondary infections, and the patient died after discharge against medical advice. Conclusion: E faecium bacteremia may cause sepsis in immunocompromised patients, and has a high mortality rate. Careful pathogen detection and early initiation of treatment is crucial to good patient outcome. |
| Databáze: | OpenAIRE |
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