Perineural Dextrose and Corticosteroid Injections for Ulnar Neuropathy at the Elbow: A Randomized Double-blind Trial
| Autor: | Tsung-Ying Li, Yu-Chi Su, Tsung-Yen Ho, Chia-Kuang Tsai, Liang-Cheng Chen, Yu-Ping Shen, Yung-Tsan Wu |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male 030506 rehabilitation Triamcinolone acetonide Visual analogue scale Elbow Anti-Inflammatory Agents Neural Conduction Pain Physical Therapy Sports Therapy and Rehabilitation Triamcinolone Acetonide Ulnar neuropathy law.invention Injections Upper Extremity 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Double-Blind Method law Surveys and Questionnaires Medicine Humans Paresthesia Prospective Studies Carpal tunnel syndrome Ulnar nerve Ulnar Nerve Aged Pain Measurement Ultrasonography Dysesthesia business.industry Rehabilitation Middle Aged medicine.disease medicine.anatomical_structure Glucose Anesthesia Female medicine.symptom 0305 other medical science business Ulnar Neuropathies 030217 neurology & neurosurgery medicine.drug Follow-Up Studies |
| Zdroj: | Archives of physical medicine and rehabilitation. 101(8) |
| ISSN: | 1532-821X |
| Popis: | Objective To assess the effects of perineural corticosteroid and 5% dextrose water (D5W) injections in patients with mild to moderate ulnar neuropathy at the elbow (UNE). Design Prospective, randomized, double-blind, controlled trial (6-month follow-up). Setting Outpatients of local medical center settings. Participants Patients (N=36) with mild to moderate UNE were randomized, and 33 participants were included in the final data analysis. Interventions Patients were administered a single perineural injection with 5 mL D5W and 3 mL corticosteroid (triamcinolone acetonide, 10mg/mL) mixed with 2 mL normal saline under ultrasound guidance in the dextrose and steroid groups, respectively. Main Outcome Measures The visual analog scale digital pain or paresthesia/dysesthesia score was the primary outcome. The secondary outcomes were the Disabilities of the Arm, Shoulder, and Hand questionnaire, motor nerve conduction velocity, and cross-sectional area (CSA) of the ulnar nerve. The measurement assessment was conducted before and 1, 3, 4, and 6 months after injection. Results Thirty-three patients completed the study. Both injections were found to be equally effective at most measurement points, although the dextrose group experienced larger reductions in symptom severity and CSA of the ulnar nerve from the third month onward. Conclusions We suggest D5W as a more suitable injectate for perineural injection in patients with UNE. |
| Databáze: | OpenAIRE |
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