Change in ischemia-modified albumin and its clinical significance during exercise stress testing
| Autor: | Ho-Joong Youn, Hun-Jun Park, Hae Kyung Lee, Seung-Won Lee, CM Kim, Dong-Hyeon Lee, Hui-Kyung Jeon, Woo-Seung Shin |
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| Rok vydání: | 2010 |
| Předmět: |
Exercise stress testing
Adult Male medicine.medical_specialty Chest Pain Myocardial Ischemia Duke treadmill score Chest pain Severity of Illness Index Coronary artery disease Bruce protocol Predictive Value of Tests Internal medicine medicine Humans Clinical significance Exercise Serum Albumin Aged business.industry Ischemia-modified albumin food and beverages Exercise stress General Medicine Middle Aged medicine.disease Surgery Dyspnea Cardiology Exercise Test Regression Analysis Female medicine.symptom Cardiology and Cardiovascular Medicine business Biomarkers |
| Zdroj: | Circulation journal : official journal of the Japanese Circulation Society. 74(3) |
| ISSN: | 1347-4820 |
| Popis: | BACKGROUND There is little data about the additive effects of ischemia-modified albumin (IMA) on the exercise stress test (EST) used for the screening of ischemic heart disease. The relationship between myocardial ischemic burden and the change in IMA (DeltaIMA) during EST was investigated. METHODS AND RESULTS EST was performed using the Bruce protocol to evaluate chest pain or exertional dyspnea in 155 patients (men 89, 53+/-13 years). Blood samples for IMA were obtained before and immediately after EST. According to the EST results and the pattern of DeltaIMA, patients were categorized into 3 groups (none was classified as EST(-)/DeltaIMA(+)): (1) (EST(-); (2) EST(+)/DeltaIMA(-); and (3) EST(+)/DeltaIMA(+). After EST, 60 of 155 (38.7%) patients were EST(+) and 14/60 (23.3%) were EST(+)/DeltaIMA(+). Duke treadmill score was significantly lower in the EST(+)/DeltaIMA(+) group compared with the other groups (-9.0+/-7.9, -1.7+/-4.2, 6.7+/-4.4, respectively, P |
| Databáze: | OpenAIRE |
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