The causal role of the left parietal lobe in facilitation and inhibition of return
| Autor: | Ana B. Chica, G. Marino, Elisa Martín-Arévalo, Itsaso Colás, Cristina Narganes-Pineda, Juan Lupiáñez |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Cognitive Neuroscience medicine.medical_treatment Experimental and Cognitive Psychology Stimulation 050105 experimental psychology Functional Laterality Inhibition of return 03 medical and health sciences Young Adult 0302 clinical medicine Parietal Lobe medicine Reaction Time Humans 0501 psychology and cognitive sciences Attention Association (psychology) Cued speech 05 social sciences Parietal lobe Electroencephalography Transcranial Magnetic Stimulation White Matter Peripheral Transcranial magnetic stimulation Inhibition Psychological Neuropsychology and Physiological Psychology Facilitation Cues Psychology Neuroscience 030217 neurology & neurosurgery Photic Stimulation |
| Zdroj: | Cortex; a journal devoted to the study of the nervous system and behavior. 117 |
| ISSN: | 1973-8102 |
| Popis: | Following non-informative peripheral cues, responses are facilitated at the cued compared to the uncued location at short cue-target intervals. This effect reverses at longer intervals, giving rise to Inhibition of Return (IOR). The integration-segregation hypothesis (Lupianez, 2010) suggests that peripheral cues always produce an onset-detection cost regardless the behavioral cueing effect that is measured – either facilitation or IOR. In the present study, we used transcranial magnetic stimulation (TMS) to investigate the causal contribution of this detection cost to performance. We used a cueing paradigm with a target discrimination task that was preceded by a non-informative peripheral cue. The presence-absence of a central intervening event was manipulated. Online TMS to the left superior parietal lobe (compared to an active vertex stimulation) lead to an overall more positive effect (faster responses for cued as compared to uncued trials), by putatively impairing the detection cost contribution to performance. The data revealed a strong association between overall RT and the TMS effect, and also between overall RT and the integrity of the first branch of the left superior longitudinal fascicule. These results have critical implications not only for the open debate about the mechanism/s underlying spatial orienting effects, but also for the growing literature demonstrating that white matter connectivity is crucial for explaining inter-individual behavioral variability. |
| Databáze: | OpenAIRE |
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