Scintigraphic evaluation of childhood malignancies by 67Ga-citrate
| Autor: | John W. Moohr, Ronald B. Port, Jeffry K. Kranzler, Emily Pang, Carlos Bekerman |
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| Rok vydání: | 1978 |
| Předmět: |
Male
medicine.medical_specialty Soft Tissue Neoplasm Adolescent Lymphoma Radiography Bone Neoplasms Gallium Radioisotopes Soft Tissue Neoplasms Neuroblastoma Neoplasms Medicine Humans Radiology Nuclear Medicine and imaging Child Radionuclide Imaging Lung business.industry Infant Sarcoma medicine.disease Hodgkin Disease Primary bone Isotopes of gallium medicine.anatomical_structure Child Preschool Female Radiology business Nuclear medicine |
| Zdroj: | Radiology. 127(3) |
| ISSN: | 0033-8419 |
| Popis: | The utility and limitations of 67Ga scintigraphy in children with solid tumors were evaluated. Thirty-five patients with malignancies (13 lymphoreticular neoplasms, 11 soft-tissue sarcomas, 8 neuroblastomas, and 3 primary bone tumors) had a 67Ga-citrate scan as part of their clinical evaluation. The sensitivity and specificity of the test were analyzed for the different tumor types. The overall sensitivity of the 67Ga-citrate scan for the lymphoma group was 87%. Higher values were obtained for the mediastinal and abdominal regions. Ninety-three per cent of the involved sites were correctly identified by 67Ga scintigraphy in the soft-tissue sarcoma group. Small lung metastases, however, were missed on scan. Thus, 67Ga scans should be complemented with chest radiographs and whole chest tomograms for both initial evaluation and follow-up in those patients. 67Ga had low sensitivity for neuroblastoma. |
| Databáze: | OpenAIRE |
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