The role of red cell distribution width as a noninvasive index for predicting liver cell failure and portal hypertension in cirrhotic patients
| Autor: | Marina A. Waheeb, Tarek A. Hassan, Howaida Nafady, Lobna Abdel-Wahid Ahmed |
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| Rok vydání: | 2018 |
| Předmět: |
lcsh:Internal medicine
medicine.medical_specialty Cirrhosis complete blood count (CBC) Encephalopathy Population 030204 cardiovascular system & hematology prothrombin time (PT) international normalization ratio (INR) 03 medical and health sciences liver cell failure (LCF) model for end stage liver disease (MELD) 0302 clinical medicine Internal medicine liver cirrhosis (LC) medicine lcsh:RC31-1245 education portal vein (PV) red blood cell distribution width (RDW) education.field_of_study business.industry Liver cell Red blood cell distribution width Cirrhotic patient liver function test (LFT) medicine.disease red blood corpusles (RBCs) Increased risk Cardiology Portal hypertension 030211 gastroenterology & hepatology business |
| Zdroj: | The Egyptian Journal of Internal Medicine, Vol 30, Iss 4, Pp 255-263 (2018) |
| ISSN: | 2090-9098 1110-7782 |
| DOI: | 10.4103/ejim.ejim_52_18 |
| Popis: | The liver distortion that occurs in cirrhosis results in increased resistance to portal blood flow and hence in portal hypertension which is one of the most common and serious complications of liver cirrhosis.Red cell distribution width (RDW) is routinely performed as part of a complete blood cell counts. Elevated RDW values were also shown to be associated with increased risk of mortality in the general population. However, to our knowledge, the role of RDW values predicting LCF and portal hypertension in LC has not been well-defined. The present study was designed to investigate the role of RDW as anon invasive predicting index for LCF and portal hypertension in cirrhotic patient which will improve the diagnostic efficiency and provide useful information with other serum markers for the detection of LCF in LC. We found significantly good correlation between Child–Pugh and RDW values which can ultimately be used to predict the survival of patients with LC. There was also good correlation between RDW and those receiving ?-blockers, so it may be used as an indicator for patient compliance, but there was no significant correlation with the grade of encephalopathy and portal hypertension. |
| Databáze: | OpenAIRE |
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