Pulmonary Alveolar Proteinosis—A New Disease?

Autor: Wallace L. Chambers, Wesley E. Peltzer, Shelley A. Swift, Henry P. Plenk
Rok vydání: 1960
Předmět:
Zdroj: Radiology. 74:928-938
ISSN: 1527-1315
0033-8419
DOI: 10.1148/74.6.928
Popis: Pulmonary alveolar proteinosis was described and named, in 1958, by Rosen, Castleman, and Liebow (8), who personally observed 2 cases and examined slides from 25 others sent to them for consultation. Two of our cases were included in this series. One additional case report has been published by Moertel, Woolner, and Bernatz (5), and 2 examples were recently reported by Lull et al. (4). Brief mention of 2 cases was also made in a Veterans Administration-United States Army report (7). One other proved case has come to our attention (9). This brings the total number of proved cases, including the 4 examples to be presented in this paper, to 35. The disease is always confined to the lung and is characterized histologically by the presence of extensive granular eosinophilic material which fills and sometimes distends the normal alveoli. This material stains positively with periodic acid Schiff stain (PAS positive) indicating the presence of mucopolysaccharides. The alveolar walls are usually unaffected, though...
Databáze: OpenAIRE