Chronic thromboembolic pulmonary hypertension in patients with persistent chest symptoms after acute pulmonary embolism
| Autor: | Esin Tuncay, Dilek Kanmaz, Zeki Öngen, Esin Yentürk, Elif Sahutoglu, Hurrem Gul Ongen, Gülfidan Aras |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty pulmonary embolism Adolescent Hypertension Pulmonary Hemodynamics 030204 cardiovascular system & hematology chronic thromboembolic pulmonary hypertension 03 medical and health sciences Young Adult 0302 clinical medicine Internal medicine Diseases of the circulatory (Cardiovascular) system Medicine Humans In patient right heart catheterization Aged Original Investigation Aged 80 and over medicine.diagnostic_test business.industry Ventilation/perfusion scan Middle Aged medicine.disease Pulmonary hypertension Pulmonary embolism 030228 respiratory system ventilation-perfusion scan Echocardiography RC666-701 Acute Disease Chronic Disease Cardiology Breathing Chronic thromboembolic pulmonary hypertension Female Cardiology and Cardiovascular Medicine business Perfusion |
| Zdroj: | Anatolian Journal of Cardiology Anatolian Journal of Cardiology, Vol 25, Iss 1, Pp 24-29 (2021) |
| ISSN: | 2149-2271 |
| Popis: | Objective This study aimed to analyze the role of chronic thromboembolic pulmonary hypertension (CTEPH) in patients with persistent chest symptoms after acute PE. Methods Patients aged between 18 and 80 years who were followed up for acute PE were screened for chest symptoms which persisted after the anticoagulation treatment. Patients suffering other types of pulmonary hypertension (PH) or metastatic malignancies were excluded in this study. Demographic and functional data of patients included this study were collected. The patients underwent transthoracic echocardiography and ventilation/perfusion (VQ) scans. Also, invasive hemodynamic studies were done to patients with intermediate/high probability of VQ scans. Results Of the 140 patients screen for this study, 29 patients (Female/Male=16/13) with mean age of 56.1±11.2 years and follow-up time of 35.1±17.7 months met the inclusion criteria. The mean systolic pulmonary artery blood pressure (sPAP) on transthoracic echocardiography was 28.9±4.9 mm Hg (range=20-40 mm Hg). Furthermore, intermediate or high probability of VQ scans was detected in 2 patients, who were subsequently diagnosed with CTEPH (6.9%) via right heart catheterization. Conclusion CTEPH was diagnosed at a low rate in patients with persistent chest symptoms after the anticoagulation treatment for PE. CTEPH is still an elusive entity, which requires a multidisciplinary and invasive approach. |
| Databáze: | OpenAIRE |
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