SEX OF FIRST CHILD AS A PROGNOSTIC FACTOR IN BREAST CANCER
| Autor: | P. Juret, Vernhes Jc, Leplat G, T. Delozier, A.M. Mandard, Couette Je |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Male
medicine.medical_specialty Prognostic factor Time Factors medicine.medical_treatment media_common.quotation_subject Population Breast Neoplasms First birth Sex Factors Breast cancer Humans Medicine Sex Ratio Girl education Mastectomy media_common Gynecology Fetus education.field_of_study business.industry Obstetrics Female sex General Medicine Prognosis medicine.disease Lymphatic Metastasis Female France Birth Order business Follow-Up Studies |
| Zdroj: | The Lancet. 311:415-416 |
| ISSN: | 0140-6736 |
| DOI: | 10.1016/s0140-6736(78)91204-7 |
| Popis: | The sex of the first child of patients who underwent mastectomy for potentially curable breast cancer appeared to be a valuable prognostic factor: patients whose first child was a boy had a better outcome than those whose first child was a girl. The difference was statistically significant. This may have been because the male/female sex ratio among first children was significantly higher in those patients without node involvement than in those with node involvement. But the favourable effect of a male first birth was still seen when only patients with an equal degree of node involvement (greater than or equal to 4 nodes) were studied. The "protection" resulting from a male first-born could be the result of fetal testicular secretions. This protection did not apply to the risk of breast cancer--the male/female sex ratio of first children in our series was 1.08, a figure not statistically different from that of the overall French population (1.05). |
| Databáze: | OpenAIRE |
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