The impact of diabetes duration on left ventricular diastolic function and cardiovascular disease

Autor: Eak Kyun Shin, Jeonggeun Moon, Woong Chol Kang, Yujeong Kim, Mi-Seung Shin, Yeun Sun Kim, Bong Roung Kim, Tae Hoon Ahn, Wook-Jin Chung
Rok vydání: 2012
Předmět:
Zdroj: Postgraduate Medical Journal. 88:189-193
ISSN: 1469-0756
0032-5473
DOI: 10.1136/postgradmedj-2011-130439
Popis: Objectives The question of whether diabetes mellitus (DM) duration correlates with the severity of dysfunction has not been well studied. We hypothesised that the longer the duration of DM the worse the severity of left ventricular (LV) diastolic dysfunction and increased risk of cardiovascular disease (CVD). Methods We reviewed 547 diabetic patients between January 2005 and April 2010. Finally, 92 consecutive patients who presented with type 2 DM and who underwent echocardiographic assessment were enrolled according to the selection criteria. In all patients, ischaemic heart disease and heart failure were excluded. Results Diastolic parameters were significantly worsened with increasing duration of DM (p Conclusions Alteration of diastolic function induced by DM worsens with increasing duration of DM. DM duration on echocardiographic evaluation time did not differ significantly between the CVD incident and the non-CVD incident groups. The rate of CVD development was not significantly different if the duration of DM was more than 7 years. Therefore, active medical care including echocardiography should be undertaken to prevent CVD from the point of diagnosis of type 2 DM.
Databáze: OpenAIRE