Comparison of ThinPrep versus conventional smear cytopreparatory techniques for fine-needle aspiration specimens of head and neck masses
| Autor: | Balaram Puligandla, Barry M. Rasgon, Raul M. Cruz, William Pshea, Karen Axelsson, Thomas M. Schmidtknecht, Raymond L. Hilsinger, Lloyd C. Ford, Gregory J. Rumore, John Sawicki |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Diagnostic accuracy 03 medical and health sciences 0302 clinical medicine Medicine Humans Prospective Studies 030223 otorhinolaryngology Head and neck Child Conventional technique Aged Aged 80 and over Histocytological Preparation Techniques medicine.diagnostic_test business.industry Biopsy Needle Head neck Reproducibility of Results Consumer Behavior Middle Aged Fine-needle aspiration Otorhinolaryngology Head and Neck Neoplasms 030220 oncology & carcinogenesis Child Preschool Surgery Female Radiology business |
| Zdroj: | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 126(5) |
| ISSN: | 0194-5998 |
| Popis: | Objectives: Diagnostic accuracy of the ThinPrep process (Cytyc, Boxborough, MA) was compared with that of conventional (smear) cytopreparation for fine-needle aspiration (FNA) of head and neck masses. Methods: In a prospective, randomized, single-blinded study, 209 patients served as their own controls and underwent 236 FNAs using ThinPrep and conventional (smear) cytopreparatory techniques. Results: ThinPrep produced less air-drying artifact and less mechanical distortion than the conventional method. The conventional technique was diagnostic in 63% of samples; the ThinPrep technique was diagnostic in 55% of samples. When all results were combined, pathologists subjectively preferred the conventional technique but accepted use of ThinPrep as the only cytopreparatory technique for most head and neck masses. Conclusions: For adequately experienced cytopathologists, ThinPrep is acceptable for FNA of salivary masses, neck cysts, metastatic lymph nodes, and thyroid lesions. Conventional smear technique should be used for FNA of nonmetastatic lymphoid lesions. Use of ThinPrep can complement use of the conventional (smear) cytopreparatory technique when aspirate is nondiagnostic or bloody, when the patient has a blood-borne infectious disease, when the clinician is inexperienced, or when aspirate has entered the syringe. (Otolaryngol Head Neck Surg 2002; 126:554-61.) |
| Databáze: | OpenAIRE |
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