Web-based cognitive training for breast cancer survivors with cognitive complaints-a randomized controlled trial

Autor: RK Andreasen, Malene Flensborg Damholdt, O'Toole, Anders Degn Pedersen, Mimi Mehlsen, Robert Zachariae
Rok vydání: 2015
Předmět:
Zdroj: Psycho-Oncology
Westphael, G, Damholdt, M F, Mehlsen, M Y, OToole, M S, Andreasen, R K & Zachariae, R 2016, ' Web-based cognitive training for breast cancer survivors with cognitive complaints – a randomized controlled trial ', 5th Biennial International Cognition and Cancer Task Force Meeting, Amsterdam, Netherlands, 14/03/2016-16/03/2016 .
Aarhus University
Damholdt, M F, Mehlsen, M, O'Toole, M S, Andreasen, R K, Pedersen, A D & Zachariae, R 2016, ' Web-based cognitive training for breast cancer survivors with cognitive complaints–a randomized controlled trial ', Psycho-Oncology, vol. 25, no. 11, pp. 1293-1300 . https://doi.org/10.1002/pon.4058
ISSN: 1099-1611
DOI: 10.1002/pon.4058
Popis: Background Cognitive complaints are common amongst breast cancer survivors, and no standard treatment exists. The present study evaluates whether web-based cognitive training can alleviate subjectively reported and objectively assessed cognitive complaints in a sample of breast cancer survivors. The primary and secondary outcomes were an objective measure of working memory and a measure of perceived cognitive functioning. Additional outcomes were neuropsychological tests of memory, executive function, working memory and questionnaire-based assessment of anxiety, depression and somatization. Methods A total of 157 female breast cancer survivors were recruited from an existing cohort and through announcements in open access cancer-related Internet fora and randomly allocated to either web-based cognitive training (eCogT) with telephone support (n = 94) or a waitlist control (WLC) condition (n = 63). eCogT encompassed 30 training sessions over 6 weeks. Neuropsychological assessments were undertaken over the telephone, and questionnaire data was collected online. Data was collected at baseline, post-intervention and at 5-month follow-up. Results Mixed linear models revealed no statistically significant change in primary or secondary outcome at follow-up in either group. Statistically significant improvements (p 0.040–0.043) were found in the eCogT group for verbal learning and on a working memory test. Conclusions Web-based cognitive training did not result in improvements of the primary or secondary outcome. Improved performance was observed on verbal learning and working memory. These effects were observed at 5-month follow-up, indicating long-term effects of training. The intervention may be applied in a clinical setting at low cost and without risk of adverse effects. © 2016 The Authors. Psycho-Oncology Published by John Wiley & Sons Ltd.
Databáze: OpenAIRE
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