Working against the biological clock: a review for the Occupational Physician
| Autor: | Alfredo Copertaro, Massimo Bracci |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Night shift work
Occupational Medicine Light Biological clock Health Toxicology and Mutagenesis Review Article Desynchronization of circadian rhythms Biological clocks Rhythm Circadian Clocks Work Schedule Tolerance Medicine Humans Circadian rhythm Shift work schedule Suprachiasmatic nucleus business.industry Public Health Environmental and Occupational Health Chronobiology Disorders Health survey Rotating shift work Chronobiology disorders Master clock business Shift Work Schedule Sleep Neuroscience Anterior hypothalamus |
| Zdroj: | Industrial Health |
| ISSN: | 1880-8026 0019-8366 |
| Popis: | The master clock of the biological rhythm, located in the suprachiasmatic nucleus of the anterior hypothalamus, synchronizes the molecular biological clock found in every cell of most peripheral tissues. The human circadian rhythm is largely based on the light-dark cycle. In night shift workers, alteration of the cycle and inversion of the sleep-wake rhythm can result in disruption of the biological clock and induce adverse health effects. This paper offers an overview of the main physiological mechanisms that regulate the circadian rhythm and of the health risks that are associated with its perturbation in shift and night workers. The Occupational Physician should screen shift and night workers for clinical symptoms related to the perturbation of the biological clock and consider preventive strategies to reduce the associated health risks. |
| Databáze: | OpenAIRE |
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