Do Wound Cultures Give Information About the Microbiology of Blood Cultures in Severe Burn Patients?
| Autor: | Ron Fishel, Dana Egozi, Tanya Mashiach, Yehuda Ullmann, Ayelet Raz-Pasteur, Emilia Hardak |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Databases Factual Burn Units Bacteremia Microbial Sensitivity Tests Risk Assessment Severity of Illness Index Sepsis Cohort Studies 03 medical and health sciences 0302 clinical medicine Injury Severity Score Flora (microbiology) medicine Confidence Intervals Humans Severe burn 030212 general & internal medicine Israel Intensive care medicine Fungemia Aged Retrospective Studies Burn wound Chi-Square Distribution business.industry 030208 emergency & critical care medicine Retrospective cohort study Middle Aged bacterial infections and mycoses medicine.disease Anti-Bacterial Agents Wound Infection Surgery Female business Burns human activities |
| Zdroj: | Annals of plastic surgery. 76(1) |
| ISSN: | 1536-3708 |
| Popis: | Blood stream infection (BSI) and the subsequent development of sepsis are among the most common infection complications occurring in severe burn patients. This study was designed to evaluate the relationship between the burn wound flora and BSI pathogens.Documentation of all bacterial and fungal wound and blood isolates from severe burn patients hospitalized in the burn unit and intensive care unit was obtained from medical records retrieved retrospectively from a computerized, hospital-wide database over a 13-year period. All data were recorded in relation to the Ryan score.Of 195 severe burn patients, 88 had at least 1 BSI episode. Transmission of the same pathogen from wound to blood was documented in 30% of the patients, with a rising BSI frequency as the Ryan score increased. There were a total of 263 bacteremic episodes in 88 study patients, 44% of blood isolates were documented previously in wound cultures, and transmission of the same pathogen from wound to blood was noted in 65% of bacteremic patients.When there is clinical suspicion of sepsis, appropriate empirical systemic antibiotic therapy should be broad spectrum and should rely on the susceptibility of the organisms from recent cultures of the burn wound surface, until the blood cultures results are completed. |
| Databáze: | OpenAIRE |
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