Immune reconstitution inflammatory syndrome associated with PML in AIDS: a treatable disorder

Autor:	M. Martinez, Gustavo Sevlever, Z. Salazar Salazar, R. Jordan, Ernesto D Efrón, M. M. Fernandez Pardal, J. V. Martinez, Ricardo Reisin, Pablo Bonardo, Sergio C Verbanaz, Julieta Mazziotti
Rok vydání:	2006
Předmět:	Adult Male Pathology medicine.medical_specialty T-Lymphocytes Anti-Inflammatory Agents Hemiplegia Dexamethasone Central nervous system disease Immune reconstitution inflammatory syndrome Immunopathology Antiretroviral Therapy Highly Active medicine Aphasia Humans Sida Inclusion Bodies Acquired Immunodeficiency Syndrome Slow virus medicine.diagnostic_test biology business.industry Progressive multifocal leukoencephalopathy Brain biopsy Macrophages Leukoencephalopathy Progressive Multifocal virus diseases Brain medicine.disease biology.organism_classification JC Virus Magnetic Resonance Imaging Chemotaxis Leukocyte Oligodendroglia Treatment Outcome Withholding Treatment Immunology Encephalitis Neurology (clinical) Viral disease business
Zdroj:	Neurology. 67(9)
ISSN:	1526-632X
Popis:	An HIV-1-infected patient with progressive multifocal leukoencephalopathy presented clinical deterioration and contrast-enhancing lesions on brain nuclear MR after the initiation of highly active antiretroviral therapy (HAART). Brain biopsy identified an inflammatory reaction compatible with immune reconstitution inflammatory syndrome. Treatment with corticosteroids and transient suppression of HAART led to marked neurologic improvement.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3187e45188d7fd5fa6d1f4aa4501ab8 https://pubmed.ncbi.nlm.nih.gov/17101910 Zobrazit plný text záznamu