Efficacy of oral terbinafine in feline dermatophytosis due to Microsporum canis
| Autor: | Leonardo Guarnieri, Francesca Mancianti, Francesca Pedonese, Francesca Millanta |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Male
medicine.medical_specialty Antifungal Agents Itraconazole Administration Oral Naphthalenes Cat Diseases medicine.disease_cause Griseofulvin chemistry.chemical_compound Animals Dermatomycoses Microsporum Medicine Microsporum canis Small Animals Terbinafine CATS biology business.industry biology.organism_classification Dermatology Treatment Outcome Canis chemistry Cats Dermatophyte Female business medicine.drug |
| Popis: | Microsporum canis is the dermatophyte most commonly responsible for ringworm in cats. The purpose of this paper was to evaluate the in vivo efficacy of oral terbinafine (Lamisil; Sandoz) in the treatment of feline ringworm caused by M canis, and to consider this drug as an alternative to griseofulvin or imidazoles. Fifteen cats infected with M canis were treated orally once daily with 30 mg/kg of terbinafine over a 2-week period. All treated animals were checked for dermatophytes on the last day of treatment, a month later and 3 months after the last administration of the drug. Only 12 cats could be used in the whole trial and 11 of these (92%) showed a complete cure. Terbinafine could be an effective alternative to griseofulvin when fungal resistance or idiosyncrasic intolerance are shown and, compared with griseofulvin, could give a faster rate of cure and less relapses. |
| Databáze: | OpenAIRE |
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