High XBP1 expression is a marker of better outcome in multiple myeloma patients treated with bortezomib

Autor:	Gambella, Manuela, Rocci, Alberto, Passera, Roberto, Gay, Francesca, Omedè, Paola, Crippa, Claudia, Corradini, Paolo, Romano, Alessandra, Rossi, Davide, Ladetto, Marco, Boccadoro, Mario, Palumbo, Antonio
Jazyk:	angličtina
Rok vydání:	2014
Předmět:	Male X-Box Binding Protein 1 XBP1 Myeloma protein Antineoplastic Agents Regulatory Factor X Transcription Factors Biology Disease-Free Survival BLIMP1 Bortezomib IRF4 medicine Biomarkers Tumor Humans Letters to the Editor Transcription factor Multiple myeloma Aged Neoplastic Tumor Hematology medicine.disease Molecular biology Boronic Acids Neoplasm Proteins DNA-Binding Proteins Gene Expression Regulation Neoplastic Survival Rate medicine.anatomical_structure Gene Expression Regulation multiple myeloma biomarker Pyrazines Monoclonal Cancer research Female Bone marrow Multiple Myeloma Biomarkers medicine.drug Transcription Factors
Popis:	Multiple myeloma (MM) is a hematologic tumor characterized by accumulation of monoclonal plasma cells (PCs) in the bone marrow (BM) producing antigen-specific immunoglobulins. The transcription factor X box binding protein 1 (XBP1), the interferon regulatory factor 4 (IRF4) and the transcriptional
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2eaaeadb291556e8134bb63163e7d00 https://hdl.handle.net/20.500.11769/542317 Zobrazit plný text záznamu