Histochemical investigations on the presence of acetylcholinesterase and succinic dehydrogenase in fetal human spinal cord and brain stem at different stages of development
| Autor: | J.-C. Roches, H.R. Zumstein, Ph. Heitz, E. Hösli, P. Wolf, L. Hösli |
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| Rok vydání: | 1975 |
| Předmět: |
Pathology
medicine.medical_specialty Cord Aché Acid Phosphatase Gestational Age Biology chemistry.chemical_compound Fetus medicine Animals Cholinesterases Humans L-Lactate Dehydrogenase Succinate dehydrogenase Anatomy Spinal cord Alkaline Phosphatase Acetylcholinesterase language.human_language Rats Succinate Dehydrogenase medicine.anatomical_structure Neurology chemistry Spinal Cord In utero language biology.protein Alkaline phosphatase Neurology (clinical) Brain Stem |
| Zdroj: | European neurology. 13(1) |
| ISSN: | 0014-3022 |
| Popis: | A comparison has been made of the localization and ontogenetic development of acetylcholinesterase (AChE) and succinic dehydrogenase (SDH) in sections of fetal human apinal cord and brain stem using histochemical methods. Spinal cord sections of young fetuses (8-10 weeks in utero) showed low to moderate enzymatic activity whereas sections of older fetuses (12-18 weeks in utero) revealed high concentrations of AChE and SDH in the ventral and laeral horns. A similar increase in enzymatic activity during development was also observed in brain stem sections where AChE and SDH were mainly confined to cranial nerve nuclei. A comparison of our histochemical findings with investigations on the development of motor activity in the spinal cord suggests that there is a correlation between the increase in AChE activity and functional development. |
| Databáze: | OpenAIRE |
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