Indocyanine green can stand alone in detecting sentinel lymph nodes in cervical cancer
| Autor: | Yiran Wang, Lu Han, Xiaoqian Tuo, Qian Wu, Qiling Li, Qing Wang, Sijia Ma, Qurat Ulain, Qi Wang, Lanbo Zhao, Qing Song, Chao Sun |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Image-Guided Biopsy
Indocyanine Green Medicine (General) Pathology medicine.medical_specialty genetic structures cervical cancer Uterine Cervical Neoplasms Biochemistry 03 medical and health sciences chemistry.chemical_compound R5-920 radiocolloid technetium-99 0302 clinical medicine Humans Medicine Cervical cancer 030219 obstetrics & reproductive medicine Blue dye Sentinel Lymph Node Biopsy business.industry Biochemistry (medical) Sentinel lymph node detection Cell Biology General Medicine tracer medicine.disease body regions chemistry human serum albumin 030220 oncology & carcinogenesis blue dye Female Lymph Sentinel Lymph Node business Indocyanine green Meta-Analysis |
| Zdroj: | The Journal of International Medical Research Journal of International Medical Research, Vol 46 (2018) |
| ISSN: | 1473-2300 0300-0605 |
| DOI: | 10.1177/0300060518803041 |
| Popis: | Objectives The effectiveness of indocyanine green (ICG) dye for detecting sentinel lymph nodes (SLNs) in cervical cancer compared with other tracers is unknown. This study aimed to assess the validity of ICG dye in detecting SLNs in cervical cancer preoperatively. Methods We performed a literature search for identifying eligible articles from PubMed database using the search terms “cervical cancer”, “sentinel lymph node”, “indocyanine green”, “blue dyes”, “human serum albumin”, and “technetium-99 radiocolloid”. We performed a meta-analysis. Comparison of the overall, bilateral, and unilateral detection rates of the different tracers was the primary goal. Comparison of the false-negative rate among the tracers was the secondary goal. Results Only eight retrospective studies including 661 patients were included. ICG versus combinations of three other tracers showed significantly higher bilateral and unilateral detection rates, but no difference in the overall rate of detecting SLNs. ICG had a higher bilateral detection rate than blue dye and technetium-99. Absorbing human serum albumin into ICG as a lymphatic tracer did not show a difference in detection rate compared with ICG alone. Conclusions ICG is superior and better than other tracers, and absorbing human serum albumin as a lymphatic tracer is not required in patients with cervical cancer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|