Bleeding frequency and characteristics among hematologic malignancy inpatient rehabilitation patients with severe thrombocytopenia
| Autor: | Julie K. Silver, Eduardo Bruera, Jegy M. Tennison, Seyedeh Dibaj, Shinichiro Morishita, Jack B. Fu, Isabel M. Rutzen-Lopez |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Physical activity Hemorrhage 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Internal medicine Acute care medicine Hematologic malignancy Humans Retrospective Studies Inpatients Rehabilitation business.industry Medical record Cancer Middle Aged medicine.disease Thrombocytopenia Severe thrombocytopenia Hospitalization Oncology Hematologic Neoplasms 030220 oncology & carcinogenesis Female business Inpatient rehabilitation |
| Zdroj: | Supportive Care in Cancer. 26:3135-3141 |
| ISSN: | 1433-7339 0941-4355 |
| DOI: | 10.1007/s00520-018-4160-y |
| Popis: | To identify the frequency and characteristics of bleeding complications during acute inpatient rehabilitation of hematologic malignancy patients with severe thrombocytopenia. Retrospective descriptive analysis. Comprehensive cancer center acute inpatient rehabilitation unit. Consecutive hematologic malignancy patients with a platelet count of less than or equal to 20,000/microliter (μL) on the day of acute inpatient rehabilitation admission from 1/1/2005 through 8/31/2016. Medical records were retrospectively analyzed for demographic, laboratory, and medical data. Patients were rehabilitated using the institutional exercise guidelines for thrombocytopenic patients. Bleeding events noted in the medical record. Out of 135 acute inpatient rehabilitation admissions, 133 unique patients were analyzed with a total of 851 inpatient rehabilitation days. The mean platelet count was 14,000/μL on the day of admission and 22,000/μL over the course of the rehabilitation admission. There were 252 days of inpatient rehabilitation where patients had less than 10,000/μL platelets. A total of 97 bleeding events were documented in 77/135 (57%) admissions. Of the 97 bleeding events, 72 (74%), 14 (14%), and 11 (11%) were considered to be of low, medium, and high severity, respectively. There were 4/97 (4%) bleeding events that were highly likely attributable to physical activity but only 1/4 was considered high severity. Bleeding rates were .09, .08, .17, and .37 for > 20,000, 15–20,000, 10–15,000, and |
| Databáze: | OpenAIRE |
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