Can plant viruses cross the kingdom border and be pathogenic to humans?

Autor: Hervé Lecoq, Didier Raoult, Fanny Balique, Philippe Colson
Přispěvatelé: Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS), Unité de Pathologie Végétale (PV), Institut National de la Recherche Agronomique (INRA), Unité de Recherche sur les Maladies Infectieuses Tropicales Emergentes (URMITE), Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut Hospitalier Universitaire Méditerranée Infection (IHU Marseille), Colson, Philippe, INSB-INSB-Centre National de la Recherche Scientifique (CNRS), INSB-INSB-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48
Jazyk: angličtina
Rok vydání: 2015
Předmět:
viruses
MOTTLE-VIRUS
lcsh:QR1-502
Review
Genome
lcsh:Microbiology
Plant Viruses
phytovirus
TOBACCO-MOSAIC-VIRUS
pathogenicity
animal
interaction virus homme
TOMATO BUSHY STUNT
BEMISIA-TABACI
Vertebrate
food and beverages
santé humaine
MOVEMENT PROTEINS
DEPENDENT RNA-POLYMERASES
Agricultural sciences
3. Good health
Santé publique et épidémiologie
Infectious Diseases
Virus Diseases
Vertebrates
plant virus
kingdom
human
INSECT VECTOR
WHITEFLY VECTOR
Zoology
Plant pathology
[SDV.CAN]Life Sciences [q-bio]/Cancer
Biology
Host Specificity
pathogène humain
Immune system
LUNG-CANCER
Virology
Plant virus
biology.animal
Animals
Humans
Human virome
Arthropods
Gene
Plant Diseases
virus phytopathogène
fungi
LEAF CURL VIRUS
Mammal
Sciences agricoles
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Zdroj: Viruses
Viruses, 2015, 7 (4), pp.2074-2098. ⟨10.3390/v7042074⟩
Viruses 4 (7), 2074-2098. (2015)
Viruses, Vol 7, Iss 4, Pp 2074-2098 (2015)
Viruses, MDPI, 2015, 7 (4), pp.2074-2098. ⟨10.3390/v7042074⟩
ISSN: 1999-4915
DOI: 10.3390/v7042074⟩
Popis: International audience; Phytoviruses are highly prevalent in plants worldwide, including vegetables and fruits. Humans, and more generally animals, are exposed daily to these viruses, among which several are extremely stable. It is currently accepted that a strict separation exists between plant and vertebrate viruses regarding their host range and pathogenicity, and plant viruses are believed to infect only plants. Accordingly, plant viruses are not considered to present potential pathogenicity to humans and other vertebrates. Notwithstanding these beliefs, there are many examples where phytoviruses circulate and propagate in insect vectors. Several issues are raised here that question if plant viruses might further cross the kingdom barrier to cause diseases in humans. Indeed, there is close relatedness between some plant and animal viruses, and almost identical gene repertoires. Moreover, plant viruses can be detected in non-human mammals and humans samples, and there are evidence of immune responses to plant viruses in invertebrates, non-human vertebrates and humans, and of the entry of plant viruses or their genomes into non-human mammal cells and bodies after experimental exposure. Overall, the question raised here is unresolved, and several data prompt the additional extensive study of the interactions between phytoviruses and non-human mammals and humans, and the potential of these viruses to cause diseases in humans.
Databáze: OpenAIRE
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