| Autor: |
Lynda Chin, Jason Ernst, Alexander J. Lazar, Suhendan Ekmekcioglu, James W. Horner, Timothy P. Heffernan, Denai R. Milton, Michelle C. Barton, Elizabeth A. Grimm, Dong Yang, Amiksha Shah, Jacob B. Axelrad, Maura Williams, Neha S. Samant, Sneha Sharma, Emily Z. Keung, Chang-Jiun Wu, Petko Fiziev, Lawrence N. Kwong, Kadir C. Akdemir, Kunal Rai |
| Rok vydání: |
2023 |
| Popis: |
Supplementary Figure 1. Western blots. Supplementary Figure 2. Graphs showing tumor volume from mice following intradermal injection of (A) HMEL-BRAF^V600E cells, (B) WM115 cells, (C) 1205 Lu cells, and (D) pMEL-NRAS^G12D overexpressing GFP, RNF2 wild-type or catalytic mutant derivatives (R70C or I53S). Supplementary Figure 3. (A) RNF expression in the melanoma expression data for normal skin, nevi, and primary tumors. Supplementary Figure 4. (A) Heat map showing clustering of top 10 percent deregulated genes in duplicates of expression data from RNF2^WT overexpressing compared to GFP overexpressing HMEL-BRAF^V600E cells. Supplementary Figure 5. Chromatin state analysis on HMEL-BRAF^V600E cells. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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