The cost effectiveness of personalized dietary advice to increase protein intake in older adults with lower habitual protein intake: a randomized controlled trial

Autor: Judith E. Bosmans, Merja H. Suominen, Satu K. Jyväkorpi, Lothar D. J. Kuijper, Hanneke A.H. Wijnhoven, Ângela Jornada Ben, Ingeborg A. Brouwer, Kaisu H. Pitkälä, Marjolein Visser, Ilse Reinders, Rachel Vijlbrief, Riikka T Niskanen, Margreet R. Olthof
Přispěvatelé: APH - Health Behaviors & Chronic Diseases, APH - Aging & Later Life, Nutrition and Health, APH - Methodology, APH - Mental Health, Health Economics and Health Technology Assessment, Amsterdam Public Health, Health Sciences, Clinicum, Department of General Practice and Primary Health Care, Helsinki University Hospital Area, Teachers' Academy
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: European journal of nutrition, 61(1), 505-520. D. Steinkopff-Verlag
Reinders, I, Visser, M, Jyväkorpi, S K, Niskanen, R T, Bosmans, J E, Jornada Ben, A, Brouwer, I, Kuijper, LDJ, Olthof, M, Pitkala, K, Vijlbrief, R, Suominen, M H & Wijnhoven, H 2022, ' The cost effectiveness of personalized dietary advice to increase protein intake in older adults with lower habitual protein intake : a randomized controlled trial ', European journal of nutrition, vol. 61, no. 1, pp. 505-520 . https://doi.org/10.1007/s00394-021-02675-0
European Journal of Nutrition
ISSN: 1436-6207
Popis: Purpose To examine the cost effectiveness of dietary advice to increase protein intake on 6-month change in physical functioning among older adults. Methods In this multicenter randomized controlled trial, 276 community-dwelling older adults with a habitual protein intake n = 96), Intervention 2; similar advice and in addition advice to consume protein (en)rich(ed) foods within half an hour after usual physical activity (PROT + TIMING, n = 89), or continue the habitual diet with no advice (CON, n = 91). Primary outcome was 6-month change in 400-m walk time. Secondary outcomes were 6-month change in physical performance, leg extension strength, grip strength, body composition, self-reported mobility limitations and quality of life. We evaluated cost effectiveness from a societal perspective. Results Compared to CON, a positive effect on walk time was observed for PROT; – 12.4 s (95%CI, – 21.8 to – 2.9), and for PROT + TIMING; – 4.9 s (95%CI, – 14.5 to 4.7). Leg extension strength significantly increased in PROT (+ 32.6 N (95%CI, 10.6–54.5)) and PROT + TIMING (+ 24.3 N (95%CI, 0.2–48.5)) compared to CON. No significant intervention effects were observed for the other secondary outcomes. From a societal perspective, PROT was cost effective compared to CON. Conclusion Dietary advice to increase protein intake to ≥ 1.2 g/kg aBW/d improved 400-m walk time and leg strength among older adults with a lower habitual protein intake. From a societal perspective, PROT was considered cost-effective compared to CON. These findings support the need for re-evaluating the protein RDA of 0.8 g/kg BW/d for older adults. Trial registration The trial has been registered at ClinicalTrials.gov (NCT03712306). Date of registration: October 2018. Registry name: The (Cost) Effectiveness of Increasing Protein Intake on Physical Functioning in Older Adults. Trial Identifier: NCT03712306.
Databáze: OpenAIRE