Prevalence of metabolic disturbances among women with polycystic ovary syndrome in different regions of Brazil
| Autor: | Sylvia Asaka Yamashita Hayashida, Gustavo Arantes Rosa Maciel, Edmund Chada Baracat, Rogerio A. Lobo, Caroline P. Lopes, José Maria Soares, Vanessa Heinrich-Oliveira, Giovana De Nardo Maffazioli |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Type 2 diabetes Cohort Studies 03 medical and health sciences Young Adult 0302 clinical medicine Insulin resistance Internal medicine Diabetes mellitus parasitic diseases Glucose Intolerance medicine Prevalence Outpatient clinic Humans 030212 general & internal medicine Obesity Dyslipidemias Retrospective Studies Hypertriglyceridemia Metabolic Syndrome 030219 obstetrics & reproductive medicine business.industry nutritional and metabolic diseases Obstetrics and Gynecology General Medicine medicine.disease Polycystic ovary Phenotype Diabetes Mellitus Type 2 Female Metabolic syndrome Insulin Resistance business Dyslipidemia Brazil Polycystic Ovary Syndrome |
| Zdroj: | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and ObstetricsREFERENCES. 151(3) |
| ISSN: | 1879-3479 |
| Popis: | OBJECTIVE To describe the prevalence of metabolic disturbances in a large cohort of women with polycystic ovary syndrome (PCOS) in southeastern Brazil and to compare the findings with other cohorts of Brazilian women with PCOS. METHODS A retrospective study analyzing clinical and laboratory data of 462 women with PCOS treated at an outpatient clinic in a tertiary hospital in southeastern Brazil. Prevalence of insulin resistance, glucose intolerance, type 2 diabetes, dyslipidemia, central obesity, hypertension, and metabolic syndrome was compared to that of other cohorts of age and body mass index-matched Brazilian women with PCOS. RESULTS Women with PCOS had a median age of 25.0 (21.0-29.0) years and BMI of 28.7 (23.9-34.0) kg/m2 . Prevalence of insulin resistance, glucose intolerance, and type 2 diabetes varied from 39.6% to 55.0%, 7.2% to 28.1%, and 2.0% to 4.1%, respectively. Prevalence of central obesity, dyslipidemia due to decreased high-density lipoprotein cholesterol, hypertriglyceridemia, and metabolic syndrome ranged from 57.8% to 66.4%, 54.1% to 70.4%, 22.9% to 35.1%, and 27.4% to 38.3%, respectively, which did not differ among regions in Brazil. CONCLUSION Prevalence of metabolic disturbances was high among Brazilian women with PCOS. This study suggests that, from a public health perspective, authorities in Brazil should be aware of and encourage screening for metabolic dysfunction in women with PCOS in all regions of the country. |
| Databáze: | OpenAIRE |
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