Brain MR in patients with Langerhans cell histiocytosis: Findings and enhancement with Gd-DTPA
| Autor: | D. Komp, J. Abrahams, N S Rosenfield |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Gadolinium DTPA Male Cerebellum Pathology medicine.medical_specialty Adolescent Asymptomatic Lesion Langerhans cell histiocytosis Posterior pituitary Organometallic Compounds medicine Humans Radiology Nuclear Medicine and imaging Child Brain Diseases medicine.diagnostic_test business.industry Magnetic resonance imaging Pentetic Acid Image Enhancement medicine.disease Magnetic Resonance Imaging Histiocytosis Langerhans-Cell medicine.anatomical_structure Child Preschool Pediatrics Perinatology and Child Health Female Cerebellar atrophy medicine.symptom Tomography X-Ray Computed business Follow-Up Studies Antidiuretic |
| Zdroj: | Pediatric Radiology. 20:433-436 |
| ISSN: | 1432-1998 0301-0449 |
| Popis: | The brains of eight patient with Langerhans Cell Histiocytosis (LCH) were studied with magnetic Resonance Imaging (MRI). One scan was normal and a spectrum of abnormalities was seen in the others. Five patients had absence of the posterior pituitary bright spot, and four with evidence of pituitary dysfunction had a lesion in the region of the hypothalamus. An orbital extraconal mass was noted in one child with exopthalmus. This decreased in a follow-up study after Vinblastine therapy. The cerebellum was abnormal in two patients; the area of the dentate nuclei exhibited abnormal signal in one asymptomatic child and the MRI of another boy with a ten year history of progressive cerebellar dysfunction showed cerebral and cerebellar atrophy. Three of the five patients with deficiency of antidiuretic hormone (ADH) were studied both before and after the administration of intravenous Gadolinium-DTPA. In all three, after administration of the contrast agent, there was enhancement of involved areas. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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