Effect of Intravenous Lidocaine Infusion on Postoperative Early Recovery Quality in Upper Airway Surgery
| Autor: | Jun Wang, Chenglan Xie, Xiaojun Ding, Qiao Wang, Weibing Zhao, De Huai |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Time Factors Lidocaine medicine.medical_treatment Analgesic Palatine Tonsil Remifentanil law.invention 03 medical and health sciences Diagnostic Self Evaluation 0302 clinical medicine Randomized controlled trial Double-Blind Method 030202 anesthesiology law Paranasal Sinuses Preoperative Care medicine Clinical endpoint Humans Prospective Studies Infusions Intravenous Saline Analgesics Pain Postoperative business.industry Perioperative Middle Aged Treatment Outcome Otorhinolaryngology 030220 oncology & carcinogenesis Anesthesia Postoperative Nausea and Vomiting Female medicine.symptom Larynx business Postoperative nausea and vomiting medicine.drug |
| Zdroj: | The LaryngoscopeBIBLIOGRAPHY. 131(1) |
| ISSN: | 1531-4995 |
| Popis: | OBJECTIVES/HYPOTHESIS Systemic infusions of lidocaine have been widely used as perioperative analgesic adjuvants. The aim of this randomized, double-blinded, controlled trial was to investigate the effect of perioperative lidocaine infusion on postoperative early recovery quality in upper airway surgery. STUDY DESIGN Prospective, randomized, double-blinded, placebo-controlled trial. METHODS A total of 99 patients were randomly assigned to the lidocaine group (group L) or the control group (group C). The patients received 2 mg/kg lidocaine completed within 10 minutes before the induction of anesthesia followed by continuous infusions of 2 mg/kg/hr lidocaine (group L) or the same volume of 0.9% normal saline (group C) intravenously during anesthesia. The Quality of Recovery-40 (QoR-40) survey was administered on the preoperative day (Pre) and postoperative days 1 (POD1) and 2 (POD2). The primary endpoint was QoR-40 score on POD1 and POD2. RESULTS Compared with Pre, global QoR-40 scores on POD1 and POD2 were significantly lower (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text