Bone and Blood Vessels: The Hard and the Soft of Hematopoietic Stem Cell Niches
Autor: | Russell Garrett, Stephen G. Emerson |
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Rok vydání: | 2009 |
Předmět: |
Myelopoiesis
Osteoblasts Lymphopoiesis Mesenchymal stem cell Niche Hematopoietic stem cell Osteoblast Cell Biology Biology Hematopoietic Stem Cells Bone and Bones Cell biology Haematopoiesis medicine.anatomical_structure Immunology medicine Genetics Animals Blood Vessels Humans Molecular Medicine Stem Cell Niche Stem cell |
Zdroj: | Cell Stem Cell. 4(6):503-506 |
ISSN: | 1934-5909 |
DOI: | 10.1016/j.stem.2009.05.011 |
Popis: | Osteoblasts are important regulators of myelopoiesis and lymphopoiesis, producing several necessary soluble and membrane-associated factors. In addition, they may play important roles, along with other mesenchymal populations, in constructing an environment that is suitable for development of sinusoidal niches capable of supporting hematopoietic stem cells. |
Databáze: | OpenAIRE |
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