Hepatitis E autochthonous infection in chronic liver disease
| Autor: | Salceda Fernandez-Barredo, Samreen Ijaz, Richard P. Bendall, Malcolm Banks, Harry R. Dalton, Gabrielle L. Lockwood |
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| Rok vydání: | 2008 |
| Předmět: |
Liver Cirrhosis
Male medicine.medical_specialty Cirrhosis Sus scrofa medicine.disease_cause Chronic liver disease Fatal Outcome Hepatitis E virus Zoonoses Internal medicine medicine Animals Humans Hepatitis Hepatology Zoonotic Infection business.industry Gastroenterology Middle Aged medicine.disease Hepatitis E Superinfection Chronic Disease Immunology Viral disease business |
| Zdroj: | European Journal of Gastroenterology & Hepatology. 20:800-803 |
| ISSN: | 0954-691X |
| DOI: | 10.1097/meg.0b013e3282f1cbff |
| Popis: | Hepatitis E virus is endemic in many parts of the developing world and causes a self-limiting hepatitis in young adults, except in pregnant women and patients with chronic liver disease, where the mortality is high. Locally acquired hepatitis E is increasingly recognized in the developed world. It is caused by hepatitis E virus genotype 3, affects the middle-aged and the elderly, and may be a zoonotic infection from pigs. We present a case of locally acquired hepatitis E infection in a patient with previously undiagnosed cirrhosis, which resulted in subacute liver failure and death. We describe our attempt to trace this infection to a free-range pig farm adjacent to the patient's place of employment. Hepatitis E infection should be considered in the differential diagnosis in patients with decompensated chronic liver disease whatever their age or travel history. When found, the prognosis may be poor. |
| Databáze: | OpenAIRE |
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