Factors associated with fluctuations in repeated measurements of intraocular pressure using the Goldmann applanation tonometer in Japanese patients with primary open-angle glaucoma

Autor: Motohiro Shirakashi, Kiyoshi Yaoeda, Atsushi Miki, Atsushi Fukushima, Takeo Fukuchi
Rok vydání: 2018
Předmět:
Zdroj: Clinical Ophthalmology (Auckland, N.Z.)
ISSN: 1177-5483
Popis: Kiyoshi Yaoeda,1,2 Atsushi Fukushima,1 Motohiro Shirakashi,3 Atsushi Miki,4 Takeo Fukuchi2 1Department of Ophthalmology, Yaoeda Eye Clinic, Nagaoka, Niigata, Japan; 2Division of Ophthalmology and Visual Sciences, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Niigata, Japan; 3Department of Ophthalmology, Kido Eye Clinic, Niigata, Niigata, Japan; 4Department of Ophthalmology, Kawasaki Medical School, Kurashiki, Okayama, Japan Purpose: The aim of this study was to determine whether fluctuations in intraocular pressure (IOP) occur as a result of the order of IOP measurements or successive IOP measurements in patients with glaucoma and, if so, identify the factors causing these fluctuations.Patients and methods: Four hundred twenty-eight eyes of 214 Japanese patients with primary open-angle glaucoma (POAG) were enrolled. Patients treated with beta-blockers or prostaglandin analogs alone were included. Additionally, in the IOP measurements by noncontact tonometer, the same cases of IOP of the right and left eyes prior to this study were included in this study. Four successive IOP measurements were carried out using a Goldmann applanation tonometer as follows: IOP was measured in the first eye (right or left) and then in the fellow eye and IOP was again measured in the first eye and then in the fellow eye. Repeated-measures analysis of variance was used to test the differences in IOP between successive measurements. Generalized linear mixed models were used to test differences in IOP measurements between the right and the left eyes on repeated applanation tonometry and according to the order of measurement. Conditional binomial logistic regression analysis was used to identify factors associated with fluctuating repeated applanation tonometry measurements. A P-value of
Databáze: OpenAIRE