Accessing p ‐Hydroxycinnamic Acids: Chemical Synthesis, Biomass Recovery, or Engineered Microbial Production?

Autor: Arnaud Haudrechy, Jean-Hugues Renault, Florent Allais, Jeanne Combes, Kévin Magnien, Claire Bailly-Maitre-Grand, Amandine L. Flourat
Přispěvatelé: Agro-Biotechnologies Industrielles (ABI), AgroParisTech, Institut de Chimie Moléculaire de Reims - UMR 7312 (ICMR), SFR Condorcet, Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS)-Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS)-SFR CAP Santé (Champagne-Ardenne Picardie Santé), Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Université de Reims Champagne-Ardenne (URCA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
Rok vydání: 2020
Předmět:
[SDV.BIO]Life Sciences [q-bio]/Biotechnology
Coumaric Acids
Bioconversion
Phenylalanine
General Chemical Engineering
Biomass
Lignocellulosic biomass
Saccharomyces cerevisiae
02 engineering and technology
010402 general chemistry
01 natural sciences
Chemical synthesis
12. Responsible consumption
Ferulic acid
chemistry.chemical_compound
Biosynthesis
Escherichia coli
Caffeic acid
Environmental Chemistry
Lignin
Organic chemistry
sinapic acid
[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering
General Materials Science
Microwaves
Molecular Structure
Plant Extracts
[CHIM.ORGA]Chemical Sciences/Organic chemistry
Plants
021001 nanoscience & nanotechnology
p-hydroxycinnamic acid
0104 chemical sciences
General Energy
chemistry
Benzaldehydes
Tyrosine
coumaric acid
caffeic acid
0210 nano-technology
ferulic acid
Zdroj: ChemSusChem
ChemSusChem, ChemPubSoc Europe/Wiley, 2021, 14 (1), pp.118-129. ⟨10.1002/cssc.202002141⟩
ISSN: 1864-564X
1864-5631
DOI: 10.1002/cssc.202002141
Popis: International audience; p‐Hydroxycinnamic acids (i. e., p‐coumaric, ferulic, sinapic, and caffeic acids) are phenolic compounds involved in the biosynthesis pathway of lignin. These naturally occurring molecules not only exhibit numerous attractive properties, such as antioxidant, anti‐UV, and anticancer activities, but they also have been used as building blocks for the synthesis of tailored monomers and functional additives for the food/feed, cosmetic, and plastics sectors. Despite their numerous high value‐added applications, the sourcing of p‐hydroxycinnamic acids is not ensured at the industrial scale except for ferulic acid, and their production cost remains too high for commodity applications. These compounds can be either chemically synthesized or extracted from lignocellulosic biomass, and recently their production through bioconversion emerged. Herein the different strategies described in the literature to produce these valuable molecules are discussed.
Databáze: OpenAIRE
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