An unusual cause of posterior fossa mass: Lhermitte-Duclos disease
| Autor: | Münevver Büyükpamukçu, Nejat Akalan, Begül Yağcı-Küpeli, M. Asım Bilen, Bilgehan Yalçın, Kader Karli Oguz |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Pathology
medicine.medical_specialty Lhermitte–Duclos disease Magnetic Resonance Spectroscopy Adolescent Posterior fossa Signs and symptoms Neurosurgical Procedures Muscle hypertrophy Pathogenesis Cerebellum Medicine Humans Cerebellar Neoplasms Fourth Ventricle medicine.diagnostic_test business.industry Headache Magnetic resonance imaging Granule cell medicine.disease Dysplastic Cerebellar Gangliocytoma Magnetic Resonance Imaging medicine.anatomical_structure Treatment Outcome Neurology Cranial Fossa Posterior Female Neurology (clinical) Intracranial Hypertension business Hamartoma Syndrome Multiple Tomography X-Ray Computed Hydrocephalus |
| Zdroj: | Journal of the neurological sciences. 290(1-2) |
| ISSN: | 1878-5883 |
| Popis: | Lhermitte-Duclos disease (LDD) (dysplastic cerebellar gangliocytoma) is a rare disorder of unknown pathogenesis, presenting with signs and symptoms resulting from obstruction of cerebrospinal fluid flow and mass effect in the posterior fossa. Magnetic resonance imaging is the diagnostic modality of choice allowing preoperative diagnosis with characteristic findings. Surgery is the choice of treatment. The typical histopathological findings of LDD are characterized by widening of the molecular layer, absence of the Purkinje cell layer and hypertrophy in the granule cell layer. Herein we report an adolescent girl with LDD diagnosed preoperatively by the conventional and advanced MR techniques. |
| Databáze: | OpenAIRE |
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