Focal atrichia: A diagnostic clue in female pattern hair loss
| Autor: | Elise A. Olsen, David A. Whiting |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Central centrifugal cicatricial alopecia medicine.medical_specialty Adolescent Biopsy Dermatology Telogen effluvium Young Adult 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine otorhinolaryngologic diseases Humans Medicine Aged integumentary system medicine.diagnostic_test business.industry Frontal fibrosing alopecia Alopecia Middle Aged medicine.disease Hair loss medicine.anatomical_structure 030220 oncology & carcinogenesis Hair Disorder Scalp Vellus hair Female sense organs business Hair Follicle |
| Zdroj: | Journal of the American Academy of Dermatology. 80:1538-1543.e1 |
| ISSN: | 0190-9622 |
| Popis: | Background Focal atrichia is a common clinical finding in female pattern hair loss, the specificity and histologic findings of which need further clarification. Objective To determine the frequency of focal atrichia in various types of hair loss and its histologic characteristics in female pattern hair loss. Methods Part 1 of the study was a review of 250 consecutive female patients seen with hair loss for the presence of focal atrichia, and part 2 examined paired biopsy specimens from haired areas versus those from areas with focal atrichia in 18 subjects with female pattern hair loss. Results Focal atrichia was seen in 46 of 104 of women with female pattern hair loss (44%), including 67% of those with the late-onset subtype versus 15% of those with the early-onset subtype, compared with in 3 of 146 of those with other hair disorders (2%). Biopsy findings of focal atrichia in female pattern hair loss showed primarily a more progressive miniaturization process than that of haired areas of the scalp. Limitations Some women with female pattern hair loss may have had concomitant chronic telogen effluvium. Conclusions When present, focal atrichia is a clinical clue to the diagnosis of female pattern hair loss, particularly the late-onset subtype. |
| Databáze: | OpenAIRE |
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